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UK Cosmetic Regulation Update: Alignment with EU Standards

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  • Information Letter 136

October 2024 - UK cosmetic regulation amendment to align further with EU cosmetic regulation​

On October 3rd, the UK has notified the World Trade Organization (WTO) with a draft “Cosmetic Products (Restriction of Chemical Substances) (No. 2) Regulations 2024” that will bring the UK cosmetic regulation closer in line with the one of the European Union.

This amendment includes a ban on certain CMR (Carcinogenic, Mutagenic, or Reprotoxic) classified substances that are either already banned by the EU Cosmetic Regulation or will be banned under the upcoming Omnibus VII regulation. Notably, DIMETHYLTOLYLAMINE (CAS 99-97-8), commonly used in nail products, will be prohibited in both regions.

Products containing these banned materials cannot be placed on the UK market from April 20th, 2025 and must be withdrawn from the UK market on October 20th, 2025 at latest.

This amendment also aligns with the EU limiting KOJIC ACID use to face and hand product only at 1% maximum.

Products not compliant with the Kojic acid restriction cannot be placed on the UK market from June 20th, 2025 and must be withdrawn from the UK market on November 1stth, 2025 at latest.

List of banned ingredients in the draft of “The Cosmetic Products (Restriction of Chemical Substances) (No. 2) Regulations 2024” (UK):

Entry
N#

Name

CAS N#

Status in the EU

1680

Tetrafluoroethylene

116-14-3

Already
banned

1681

6,6′-di-tert-butyl-2,2′-methylenedi-p-cresol;
[DBMC]

119-47-1

Already
banned

1682

(5-chloro-2-methoxy-4-methyl-3-pyridyl)(4,5,
6-trimethoxy-o-tolyl)methanone; pyriofenone

688046-61-9

Already
banned

1683

(RS)-1-{1-ethyl-4-[4-mesyl-3-(2-methoxyeth oxy)-o-toluoyl]pyrazol-5-yloxy}ethyl methyl carbonate; tolpyralate

1101132-67-5

Already
banned

1684

3-methylpyrazole

1453-58-3

Already
banned

1685

N-methoxy-N-[1-methyl-2-(2,4,6-trichloroph enyl)-ethyl]-3-(difluoromethyl)-1-methylpyra zole-4-carboxamide; Pydiflumetofen

1228284-64-7

Already
banned

1686

N-{2-[[1,1′-bi(cyclopropyl)]-2-yl]phenyl}- 3- (difluoromethyl)-1-methyl–1Hpyrazole-4-carb oxamide; Sedaxane

874967-67-6

Already
banned

1687

Thiophanate-methyl
(ISO); dimethyl (1,2- ph enylenedicarbamothioyl)biscarbamat; dimethyl 4,4 -(o-phenylene)bis(3- thioallophanate)

23564-05-8

Already
banned

1688

Mancozeb
(ISO); manganese ethylenebis(dithiocarbamate)
(polymeric) complex with zinc salt

8018-01-7

Already
banned

1689

Trinickel
disulfide; nickel subsulfide; [1] heazlewoodite [2]

12035-72-2
[1]

12035-71-1
[2]

Already
banned

1690

7-oxa-3-oxiranylbicyclo[4.1.0]heptane; 1,2-e
poxy-4-epoxyethylcyclohexane;

4-vinylcyclohexene diepoxide

106-87-6

Already
banned

1691

4-methylpentan-2-one; isobutyl methyl ketone (MIBK)

108-10-1

Already
banned

1692

Carbendazim
(ISO); methyl benzimidazole-2-ylcarbamat

10605-21-7

Already
banned

1693

Dimethomorph
(ISO); (E,Z)-4-(3-(4-
chlorophenyl)-3-(3,4- dimethoxyphenyl)acryl oyl)morpholine

110488-70-5;

(1135441-72-3)

Already
banned

1694

1,2,4-triazole

288-88-0

Already
banned

1695

Flumioxazin (ISO);
N-(7-fluoro-3,4- dihydro-3-oxo-4-prop-2-ynyl–2H-1,4-
benzoxazin-6- yl)cyclohex-1-ene-1,2- dicarboximide

103361-09-7

Already
banned

1696

Imazamox
(ISO); (RS)-2-(4-isopropyl-4-
methyl– 5-oxo-2-imidazolin-2-yl)-5- methoxymethylnicotinic acid

114311-32-9

Already
banned

1697

Thiamethoxam
(ISO); 3-(2-chloro-thiazol-5- ylmethyl)-5-
methyl[1,3,5]oxadiazinan-4-ylid
ene-N-nitroamine

153719-23-4

Already
banned

1698

Triticonazole
(ISO); (RS)-(E)-5-(4- chlorobe
nzylidene)-2,2-dimethyl-1-(1H1,2,4-triazol-1-ylmethyl)cyclopentanol

138182-18-0

Already
banned

1699

Desmedipham (ISO);
ethyl 3-phenylcarbamo yloxyphenylcarbamate

13684-56-5

Already
banned

1700

Tellurium
dioxide

7446-07-3

Already
banned

1701

Tellurium

13494-80-9

Already
banned

1702

Fluopicolide
(ISO);

2,6-dichloro-N-[3-chloro-5-(trifluoromethyl)-2- pyridylmethyl]benzamide

239110-15-7

Already
banned

1703

Daminozide
(ISO); 4-(2,2- dimethylhydrazin o)-4-oxobutanoic acid;

N-dimethylaminosuccinamic acid

1596-84-5

Already
banned

1704

Benzophenone

119-61-9

Already
banned

1705

Acetamiprid (ISO);
(1E)-N-[(6- chloropyridin-3-
yl)methyl]-N’-cyano-N-meth ylethanimidamide; (E)-N 1 -[(6- chloro-3-pyridyl)methyl]-N 2 –cyano-N 1 methylacetamidine

135410-20-7

Already
banned

1706

Theophylline;

1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

58-55-9

Already
banned

1707

N-(2-nitrophenyl)phosphoric triamide

874819-71-3

Already
banned

1708

Dibutyltin
di(acetate)

1067-33-0

Already
banned

1709

Dibutyltin
bis(2-ethylhexanoate)

2781-10-4

Already
banned

1710

Cumene

98-82-8

Already
banned

1711

Barium
diboron tetraoxide

13701-59-2

Already
banned

1712

2-ethyl-2-[[(1-oxoallyl)oxy]methyl]-1,3-
propanediyldiacrylate; 2,2- bis(acryloyloxymethyl)butyl acrylate; trimethylolpropane
triacrylate

15625-89-5

Already
banned

1713

Quinoclamine (ISO);
2-amino-3-chloro-1,4-n aphthoquinone

2797-51-5

Already
banned

1714

Pendimethalin
(ISO); N-(1-ethylpropyl)- 2,6-dinitro-3,4-xylidene

40487-42-1

Already
banned

1715

Isoflucypram (ISO);
N-(5-chloro-2-isopropyl benzyl)-N-cyclopropyl-3-(difluoromethyl)-5-
fluoro-1-methyl-1H-pyrazole-4-carboxamide

1255734-28-1

Already
banned

1716

Dimoxystrobin (ISO);
(2E)-2-{2-[(2,5- dime thylphenoxy)methyl]phenyl}-2- (methoxyimi no)-N-methylacetamide;
(E)-2- (methoxyimi no)-N-methyl-2-[a-(2,5-xylyloxy)-o-tolyl]ace tamide

149961-52-4

Already
banned

1717

2-(2-methoxyethoxy)ethanol;
diethylene glycol monomethyl ether

111-77-3

Already
banned

1718

2,2-dimethylpropan-1-ol,
tribromo derivative; 3-bromo-2,2- bis(bromomethyl)propan-1-ol

36483-57-5;

Already
banned

1522-92-5

 

1719

2,4,6-tri-tert-butylphenol

732-26-3

Already
banned

1720

Ammonium
bromide

12124-97-9

Already
banned

1721

Divanadium
pentaoxide; Vanadium pentoxide

1314-62-1

Already
banned

1722

Bentazone (ISO);
3-isopropyl-2,1,3- benzoth
iadiazine-4-one-2,2-dioxide

25057-89-0

Already
banned

1723

Margosa
extract. [from the kernels of Azadirachta indica
extracted with water and further processed with organic solvents]

84696-25-3

Already
banned

1724

Valifenalate (ISO);
methyl N-(isopropoxycar bonyl)-L-valyl-
(3RS)-3-(4-chlorophenyl)-β-alaninate

283159-90-0

Already
banned

1725

Isopyrazam (ISO);
reaction mass of 3-(difluoromethyl)-1-methyl-N- [(1RS,4SR,9
RS)-1,2,3,4-tetrahydro-9-isopropyl-1,4-
meth anonaphthalen-5-yl]pyrazole-4-carboxamide and
3-(difluoromethyl)-1-methyl-N-[(1RS,4S R,9SR)-1,2,3,4- tetrahydro-9-isopropyl-1,4-m ethanonaphthalen-5- yl]pyrazole-4-carboxamide
[>78% syn isomers ≤
15% anti isomers relative content];

881685-58-1

Already
banned

1726

Perfluoroheptanoic acid; tridecafluoroheptanoic acid

375-85-9

Already
banned

1727

4,4 -sulphonyldiphenol;
bisphenol S

80-09-1

Already
banned

1728

6-[C10-C13)-alkyl-(branched,
unsaturated)-2,5-dioxopyrrolidin-1-yl]hexanoic acid
(tetra-PSCA)

2156592-54-8

Already
banned

1729

6-[C12-18-alkyl-(branched, unsaturated)-2,5-
dioxopyrrolidin-1-yl]hexanoic acid (Penta-PSCA)

 

Already
banned

1730

[C12-18-alkyl-(branched,
unsaturated)- 2,5-dioxopyrrolidin-1-yl] hexanoic acid, sodium and
tris(2-hydroxyethyl) ammonium salts; (penta-PSCA Na-TEA)

 

Already
banned

1731

1,3,5-triazine-2,4,6-triamine;
melamine

108-78-1

Already
banned

1732

Benzyl(diethylamino)diphenylphosphonium 4-[1,1,1,3,3,3-hexafluoro-2-(4-hydroxypheny l)propan-2-yl]phenolate

577705-90-9

In
Omnibus VII

1733

Benzyltriphenylphosphonium, salt
with 4,4′-[
2,2,2-trifluoro-1-(trifluoromethyl)ethylidene] bis[phenol] (1:1)

75768-65-9

In
Omnibus VII

1734

Reaction
mass of 4,4′-[2,2,2-trifluoro-1-(trifl
uoromethyl)ethylidene]diphenol and benzyl(
diethylamino)diphenylphosphonium 4-[1,1,1,
3,3,3-hexafluoro-2-(4-hydroxyphenyl)propan -2-yl]phenolate (1:1)

 

In
Omnibus VII

1735

Reaction
mass of 4,4′-[2,2,2-trifluoro 1-(trifluoromethyl)ethylidene]diphenol and benzyltriphenylphosphonium, salt with 4,4′-[2,2,2-trifluoro-1-
(trifluoromethyl)ethyli dene]bis[phenol] (1:1)

 

In
Omnibus VII

1736

Reaction
mass of 1-(2,3-epoxypropoxy)-2,2-bis ((2,3-epoxypropoxy)methyl)
butane and 1-(2,3-epoxypropoxy)-2-((2,3-epoxypropoxy)methyl)
-2-hydroxymethyl butane

 

In
Omnibus VII

1737

4,4′-[2,2,2-trifluoro-1-
(trifluoromethyl)ethyli dene]diphenol; bisphenol AF

1478-61-1

Already
banned

1738

Transfluthrin (ISO); 2,3,5,6-tetrafluorobenzyl
trans-2-(2,2-dichlorovinyl)-3,3-dimethylcyclo
propanecarboxylate

118712-89-3

In
Omnibus VII

1739

Salts
of 2-ethylhexanoic acid

 

Already
banned

1740

Benfluralin (ISO);
N-butyl-N-ethyl-α,α,α-trif luoro-2,6-dinitro-p-toluidine

1861-40-1

In
Omnibus VII

1741

N,N-dimethyl-p-toluidine

99-97-8

In
Omnibus VII

1742

4-nitrosomorpholine

59-89-2

In
Omnibus VII

1743

3,3′-dimethylbiphenyl
4,4′-diyl diisocyanate

91-97-4

In
Omnibus VII

1744

Foramsulfuron
(ISO); 2-{[(4,6-dimethoxypyr
imidin-2-yl)carbamoyl]sulfamoyl}-4-formam ido-N,N dimethylbenzamide; 1-(4,6-dimetho
xypyrimidin-2-yl)-3-(2-dimethylcarbamoyl-5-formamidophenylsulfonyl)urea

173159-57-4

In
Omnibus VII

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Authors

  • Stéphanie is Biorius's Cosmetic Regulatory Affairs Lead and works in the cosmetic industry for almost 10 years.



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    Cosmetic Regulatory Affairs Lead

  • Christophe Brault-Chevalier is the Scientific & Regulatory Affairs Director at Biorius, bringing over 20 years of experience in the cosmetics industry. He has previously held positions at International Flavors & Fragrances Inc. (IFF) and LVMH, further enhancing his expertise in the field.



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    Scientific & Regulatory Affairs Director @ BIORIUS