Cosmetic Ingredient Review

Cosmetic Ingredient Review

Comprehensive Cosmetic Ingredient Safety Evaluations

Are you a cosmetic developer or manufacturer seeking scientific support for the safety of your cosmetic ingredients? Biorius provides scientifically backed and up-to-date evaluations for your cosmetic ingredient review. With our extensive expertise, we help you navigate the complex world of cosmetic ingredients.

You will find all the necessary information for the safety assessment of cosmetic ingredients hereunder. Biorius’ toxicological expertise is here to assist you.

Cosmetic Ingredient Review

Types of Cosmetic Ingredient Review Reports

  • Summary Report: Conclusion for each endpoint.
  • Brief Report: Description of each ingredient and a concise study for each endpoint.
  • Full Report: Detailed toxicological data and exposure assessments using in silico tools, QSAR (Quantitative Structure-Activity Relationship), read-across approaches, and TTCs (Threshold of Toxicological Concern).
Toxicological Review

Toxicological Data Review

Biorius evaluates toxicological data available in the literature, focusing on:

  • Acute toxicity
  • Local effects (eye irritation, skin irritation, skin sensitization, phototoxicity)
  • Repeated dose toxicity
  • Genotoxicity
  • Carcinogenicity
  • Reproductive/Developmental toxicity
  • Pharmacokinetics (including dermal absorption)
Consumer Safety

Ensuring Consumer Safety

We assess systemic toxicity risks via Margin of Safety (MoS). Higher MoS ratios ensure better consumer protection. We tailor exposure evaluations based on product specifics, applying QRA methodology for skin sensitizers to determine acceptable ingredient concentrations.

With its experience in regulatory toxicology, Biorius evaluates the safety of your ingredients, including the safety of your complex natural extracts.

Cosmetic Ingredient Evaluation

Evaluation Process

1. Before evaluation

    • Supplier communication
    • Composition analysis
    • Data collection and organization

2. During evaluation

  • Toxicological profiles for ingredients and raw materials
  • Test plan implementation and execution
  • Risk evaluation and management

3. After evaluation

  • Comprehensive safety evaluation and certificates

Performance Assessment

Biorius evaluates the performance of cosmetic ingredients, developing the best test plans for marketing claims.

How It Works

1. Planning and Ordering Tests

2. Analyzing Test Results

We guide you in making compliant marketing claims based on test results and ingredient concentrations.

Get in Touch

Need a piece of advice, a quotation or answers to your questions? Contact us…

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As specialists in cosmetic Regulations for more than 15 years, Biorius offers a reliable turnkey solution for placing cosmetic products in various markets:

  • First Class specialists in cosmetic regulations in Europe, the United Kingdom, the United States, and in more than 60 countries
  • 50 regulatory experts, toxicologists, pharmacists, and chemists to serve you.
  • A unique model that guarantees you both the fastest turnaround possible and high-quality services. Curious? Ask us to know more!
  • No hidden costs: Biorius does not charge you for any question, call, or meeting.
  • A best-in-class IT tool, free of charge, and saving a lot of your time.
  • More than 1,500 international clients have already chosen Biorius!
  • We evaluated more than 100,000 products and never had any compliance issues (fines, withdrawals from the market, etc.) in 15 years of existence.

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